Butaret 50 mg Tablet: Each sustained release tablet contains Butamirate Citrate BP 50 mg.
Butaret 100 ml Syrup: Each 5 ml Syrup contains Butamirate Citrate BP 7.5 mg.
Butaret 200 ml Syrup: Each 5 ml Syrup contains Butamirate Citrate BP 7.5 mg.
Butaret 15 ml Pediatric Drops: Each 1 ml pediatric drops contains Butamirate Citrate BP.
Butamirate Citrate belongs to the anti cough medicines of central action.
Mode of action:
Butaret exerts expectorant, moderate bronchodilating and anti-inflammatory action. Butamirate Citrate also increases the spirometery indexes and blood oxygenation. It is safe and non-sedating which is neither chemically nor pharmacologically related to opium alkaloids. The active metabolites of Butamirate Citrate have also antitussive action. Butaret also decreases the airway resistance.
Pharmacokinetics:
Butaret is rapidly and completely absorbed after oral administration. Maximum concentration is reached within 9 hours. Butaret is extremely protein bound and plasma elimination half life is about 13 hours.
Butaret is indicated in acute cough of any etiology, suppression of pre & post Operative cough in surgery & bronchoscopy & suppression of whooping cough.
Butaret 50 mg Tablet: Adults : 2 to 3 tablets daily at 8 to 12 hours intervals. Adolescents over 12 years age: 1- 2 tablets daily. Butaret 100 ml & 200 ml Syrup: Adults : 15 ml 4 times daily. Adolescents : 15 ml 3 times daily. Children 6-12 years: 10 ml, 3 times daily. 3-6 Years: 5 ml 3 times daily. Butaret 15 ml Pediatric Drops: Children 1-3 Years: 15 drops (0.75 ml) four times daily.
Children 2 months to 1 year: 10 drops (0.5 ml) four times daily.
Butamirate Citrate should not be used during the first trimester of pregnancy. During the remainder of , it can be used if indicated by a physician but with caution. As a general rule, for safety reason, in the absence of data on elimination of the active substance in breast milk, the benefits of Butamirate Citrate administration during breast feeding should be carefully weighed against the risks.
Overdosage: Overdose may cause nausea, vomiting, diarrhea, dizziness and hypotension. The usual emergency assistance should be taken: activated charcoal, saline laxative and symptomatic treatment should be given.
Keep out of reach of children. Store ina dry place, below 25 C temperature and protected from light.