Amprolium + Sulfaquinoxaline + Vitamin K

Each g powder contains Amprolium USP 102 mg, Sulfaquinoxaline Sodium 102 mg and Vitamin K USP 1 mg.

Cocci-Off Vet contains amprolium, a thiamine antagonist that inhibits thiamine uptake by coccidia. It acts primarily upon the first-generation schizont in the cells of the intestinal wall, preventing the differentiation of merozoites. The formulation also includes sulfaquinoxaline, which inhibits the synthesis of folic acid and para-aminobenzoic acid (PABA) in both coccidia and bacteria. Additionally, vitamin K provides antihemorrhagic activity. Plasma clotting factors VII, IX, and X depend on vitamin K3 for synthesis. These blood clotting proteins are synthesized in the liver in inactive forms and are subsequently converted to biologically active forms by vitamin K3.

Poultry:

Livestock:

Route of Administration: For oral administration only.

Or as directed by the registered veterinary physician.

With medicine: Exogenous administration of thiamine in high doses may reverse or reduce the efficacy of amprolium. With food & other: None reported.

Contraindicated in animals with impaired liver and/or renal function and hypersensitivity to amprolium and/or sulfaquinoxaline.

Common: Occasionally may cause GI or neurologic effects. Rare: At high dosages in laying hens, egg drop and in broilers, growth inhibition and polyneuritis can occur.

May cause thiamine deficiency if given at high rates.

Store in a dry place. Protect from direct sunlight. Keep all medicines out of reach of children.

Meat: 10 days, Egg: 10 days, and Poultry: 10 days; must not be consumed up to 10 days after administration of this medicine.