No Data
Xcel ® Plus is a combined preparation of Paracetamol and Caffeine. Paracetamol has analgesic and antipyretic properties with weak anti-inflammatory activity. Caffeine is an alkaloid. By intermolecularassociation with paracetamol, caffeine increases the solubility and transmembrane permeation of paracetamol. In addition, caffeine increases the pain threshold and tolerance of pain.
Adults, including the elderly and children 12 years and over: 1-2 tablets every 4 hours as required. Do not take more frequently than every 4 hours. Maximum dose is 8 tablets in 24 hours. Xcel ® Plus is not recommended for children under 12 years of age.
Alcohol and hepatotoxic agents increase liver injury risk; cimetidine, oral contraceptives, and quinolones decrease caffeine clearance; decreases lithium serum levels.
Hypersensitivity to paracetamol, caffeine, or any component of the formulation; severe hepatic impairment; severe renal impairment.
No Data
Overdose
No Data
Category B (Compatible). Paracetamol is safe in pregnancy; limit caffeine intake to <200 mg/day from all sources. Lactation: Caffeine and paracetamol appear in milk; use with moderation.
Store below 25°C in a cool, dry place. Protect from light and moisture. Keep out of reach of children.