Tynium 5 mg injection: Each 2 ml ampoule contains Tiemonium Methylsulphate INN 5 mg.
Tynium 50 mg tablet: Each coated tablet contains Tiemonium Methylsulphate INN 50 mg.
Tynium syrup: Each 5 ml syrup contains Tiemonium Methylsulphate INN 10 mg.
Tynium ® is the preparation of Tiemonium Methylsulphate. It is an antispasmodic agent with anticholinergic effects used for the relief of muscular and visceral spasms.
Tablet: The usual dosage is 2 to 6 tablets (100 to 300mg) daily in divided doses as required.
Injection: The usual dosage is 1 ampoule by slow IV or IM injection 3 times per day.
Syrup: Children: 3 mL/ kg body wt daily in 3 divided doses (10 kg baby: 2 teaspoonful 3 times daily; 15 kg baby: 3 teaspoonful 3 times daily). Adult: 5-15 mL 3 times daily.
Anticholinergic drugs (atropine, antihistamines, TCAs) produce additive antimuscarinic effects (dry mouth, urinary retention); no significant CYP450 interactions reported.
Tynium ® should not be used in the following conditions: Glaucoma (acute pain of eyeball with vision disturbances), difficulty to urinate (disorders of prostate or bladder).
Less Common: Hypotension, tachycardia (rapid administration). Rare: Urinary retention.
Overdose
Occasional retention of urine may occur in case of overdoses.
Category C. Not recommended during pregnancy unless clearly indicated by physician. Lactation: Excretion in breast milk unknown; not recommended during lactation unless advised by physician.
Store below 25°C in a cool, dry place. Protect from light and moisture. Keep away from the reach of children.