Tylace™ Effervescent Tablet: Each effervescent tablet contains Acetylcysteine USP 600 mg.
Acetylcysteine and its metabolic byproduct cysteine exert its mucolytic action through its free sulfhydryl (-SH) group, which reduces the disulfide bonds in the mucus matrix and lowers mucus viscosity.
In case of Paracetamol overdose, Acetylcysteine protects against Paracetamol overdose induced hepatotoxicity by maintaining or restoring hepatic concentrations of Glutathione. It does this by producing the Glutathione precursor L-cysteine.
Acetylcysteine is indicated as an adjunctive treatment for patients with abnormal, viscid or inspissated mucus secretions associated with conditions such as:
Adults & children above 6 years of age: 1 tablet daily (Preferably in the evening). The duration of treatment should be 5-10 days in acute treatment.
In Paracetamol overdose: Initially 140 mg/kg, followed by 70 mg/kg every 4 hours for an additional 17 doses.
Dissolve 1 tablet in a glass of water (200 ml) to drink.
After taking Acetylcysteine orally it increases the bioavailability of Amoxicillin, but shows no effect on Doxycycline and reduces the absorption of Cefalexin. Acetylcysteine seems to increase the effects of Nitroglycerin.
OVERDOSE:
Accidental overdose of Acetylcysteine may cause nausea, vomiting or diarrhea.
Pregnancy Category B: Caution should be taken in case of pregnancy & lactation while using Acetylcysteine.
Protect from light & moisture, store below 25°C. Keep all medicines out of the reach of children.