Solbion®Tablet: Each film-coated tablet contains Thiamine Mononitrate (Vitamin B1) USP 100 mg, Pyridoxine Hydrochloride (Vitamin B₆) USP 200 mg and Cyanocobalamin (Vitamin B12) USP 200 mcg.
Solbion®IM Injection: Each ampoule (3 ml) containsThiamine Hydrochloride (Vitamin B1) USP 100 mg, Pyridoxine Hydrochloride (Vitamin B₆) USP 100 mg and Cyanocobalamin (Vitamin B12) USP 1 mg.
Solbion® is a preparation of Thiamine Mononitrate/Thiamine Hydrochloride (Vitamin B1) USP, Pyridoxine Hydrochloride (Vitamin B₆) USP and Cyanocobalamin (Vitamin B12) USP. It is a combination of three water-soluble vitamins in an acceptable tablet/injectable formulation. It is formulated as a prophylactic or therapeutic nutritional supplement and it is indispensable for a normal course of nervous metabolism.
Solbion® may be administered in a dosage of 1-3 tablets daily or as directed by the registered physician. Solbion®IM Injection is injected intramuscularly (deep intragluteal). In severe cases, 1 ampoule daily until the acute symptoms subside. For milder cases and follow-up therapy, 2 or 3 ampoules per week.
Concomitant use of the combination of vitamin B1, B6 and B12 with levodopa may decrease the efficacy of levodopa.
Solbion® can be used in pregnancy and lactation.
Cyanocobalamin should not be given before a diagnosis has been fully established because of the possibility of masking symptoms of subacute degeneration of the spinal cord. Cyanocobalamin is not a suitable form of Vitamin B12 for the treatment of optic neuropathies associated with raised plasma concentrations of cyanocobalamin.
Solbion® Tablet: Do not store above 30°C. Keep away from light and wet place. Keep out of reach of children. Solbion® IM Injection: Store in a refrigerator (2°C- 8°C). Keep away from light. Keep out of reach of children.