Each ml solution contains Salbutamol sulphate BP equivalent to Salbutamol 5 mg.
Each actuation delivers Salbutamol (as Sulphate) BP 100 mcg.
Use in Labor and Delivery:
Use of Salmolin (Salbutamol) Inhalation Aerosol for relief of bronchospasm during labor should be restricted to those patients in whom the benefits clearly outweigh the risk.
Use in Lactation:
It is not known whether this drug is excreted in human milk. A decision should be made whether to dis.
Salmolin Respirator Solution is an aqueous colourless solution of Salbutamol Suptate BP. Salbutamol is a synthetic sympathomimetic agent with predominant beta-2 adrenergic activity. Salbutamol produces bronchodilation through stimulation of beta-2 adrenergic receptors in bronchial smooth muscle, thereby causing relaxation of bronchial muscle fibres.
Salmolin Respirator Solution is indicated for the treatment of acute Asthma, chronic bronchitis, emphysema and other conditions associated with airways obstruction.
By Intermittent Administration:Adult (and the elderly): Salmolin Respirator Solution 0.5-1.0 ml should be diluted to final volume of 2.0-4.0 ml with normal saline for injection. The resulting solution is inhaled from a suitably driven nebulizer until aerosol generation ceases. Using a correctly matched nebulizer and driving source this should take about 10 minutes. Salmolin Respirator Solution may be used undiluted for intermittent administration. For this 2.0 ml of the solution is placed in the nebulizer and the patient allowed to inhale until bronchodilation is achieved. This usually takes 3-5 minutes. Some adult patients may require higher doses of salbutamol upto 10 mg in which case nebulization may continue until aerosol generation ceases.
Children (under 12 years of age): 0.5 ml of the solution diluted to 2.0-4.0 ml with normal saline. Some children patients may however require higher doses upto 1.0 ml of the solution. Intermittent treatment may be repeated four times a day.
By Continuous Administration:
Salmolin Respirator Solution is diluted with normal saline for injection, 1-2 ml solution made upto 100 ml with diluent. The diluted solution is administered as an aerosol by a suitably driven nebulizer. The usual rate of administration is 1-2 mg/hour. Delivery of the aerosol may be by face mask or via an endotracheal tube. Intermittent positive pressure may be used but is rarely necessary. When there is risk of anoxia through hypoventilation, oxygen should be added to the inspired air.
Dilution: Salmolin Respirator Solution may be diluted with Sodium Chloride Injection BP (normal saline). Solutions in nebulizer should be replaced daily.
OR AS DIRECTED BY THE PHYSICIAN.
Condition.
Adults and Elderly dose.
Child dose.
Amount.
Puffs.
Amount.
Puffs.
Acute bronchospasm and intermittent episodes of asthma.
100 mcg or 200 mcg per day.
1 or 2 puffs of SALMOLIN per day.
100 mcg per day.
1 puff of SALMOLIN per day.
Chronic maintenance or prophylactic therapy.
200 mcg 3-4 times daily.
2 puffs of SALMOLIN 3-4 times daily.
100 mcg 3-4 times daily (may be increased to 200 mcg if necessary).
1 puff of SALMOLIN 3-4 times daily (may be increased to 2 puffs if necessary).
Exercise induced bronchospasm.
200 mcg before exertion.
2 puffs of SALMOLIN before exertion.
100 mcg before exertion.
1 puff of SALMOLIN before exertion.
OR AS DIRECTED BY THE PHYSICIAN.
With medicine: Salbutamol should be administered with extreme caution to patients being treated with MAO inhibitors or tricyclic antidepressants since the action of Salbutamol on the cardiovascular system may be potentiated. Beta-adrenergic blocking drugs, especially the non-cardio selective ones; may effectively antagonize the action of Sal.
Salmolin:Salbutamol (as Sulphate) BP:HFA Inhalation Aerosol:Description:
Salmolin (Salbutamol) is a beta-2-adrenoreceptor agonist. It is a hydrofluoroalkane (HFA) based environment friendly inhaler. Because it does not contain chlorofluorocarbon (CFC) as propellant which is one of the main reasons of ozone layer depletion.
Salmolin relaxes the muscles in the walls of small air passages in the lungs. Salbutamol is used in the treatment of asthma and other forms of reversible airways obstruction.
Unnecessary administration of drugs during the first trimester of pregnancy is undesirable. It is not known whether this drug is excreted in human milk. Because of the potential of tumorigenicity shown for salbutamol in some animal studies, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
Safe using in age 1 month and above for children & adolescents.
There are no adequate and well-controlled studies in pregnant women. Salbutamol should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
It should be used with care in patients known to have received large doses of other sympathomimetic drugs. It should be used with care in patients suffering from thyrotoxicosis. Salmolin Respiration Solution should be used with a respirator or nebulizer, only under the direction of a physician. Not to be injected or taken orally. Patients receiving treatment at home with Salmolin Respirator Solution should be warned that if either usually relief is diminished or the usual duration of action reduced, they should not increase the dose or its frequency of administration but seek medical advice.
Salmolin, as with all sympathomimetic amines, should be used with caution in patients with cardiovascular disorders especially coronary insufficiency, cardiac arrhythmias and hypertension in patients with convulsive disorders, hyperthyroidism, or diabetes mellitus.