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PG® 25 mg (Capsule) - Uses, Price & Generic Alternatives — Medyve

Prescription Required: Registered Medical Practitioner's prescription is required to purchase this product.

Human

PG®

Capsule

25 mg

GENERIC NAMEPregabalin

MANUFACTURED BYEskayef Pharmaceuticals Ltd.

Available Pack Sizes:3 Sizes

Purchase Option:Full Pack

Maximum Retail Price (MRP):

Quantity

৳ 90.00/ 6 x 4

1

(Unit: ৳ 10.00 / 1 Capsule)

Composition

PG® 25 Capsule: Each capsule contains Pregabalin INN 25 mg.

PG® 50 Capsule: Each capsule contains Pregabalin INN 50 mg.

PG® 75 Capsule: Each capsule contains Pregabalin INN 75 mg.

Description

PG® is the preparation of Pregabalin, used for the treatment of neuropathic pain and as an adjunctive therapy for partial seizures epilepsy. The active substance, Pregabalin, is a gamma-aminobutyric acid analogue (S)-3-(aminomethyl)-5-methylhexanoic acid. Pregabalin binds to an auxiliary subunit (α2-δ protein) of voltage-gated calcium channels in the central nervous system, potently displacing [H]- gabapentin.

Indications

Neuropathic pain: PG® is indicated for the treatment of peripheral neuropathic pain including diabetic peripheral neuropathy in adults.

Epilepsy: PG® is indicated as adjunctive therapy in adults with partial seizures with or without secondary generalization.

Fibromyalgia.

Post Herpetic Neuralgia.

Generalized Anxiety Disorder.

Dosage & Administration

The dose range is 150 to 600 mg per day given in either two or three divided doses.

PG® may be taken with or without food.

Neuropathic pain:

Administer in 3 divided doses per day.

Begin dosing at 150 mg per day.

May be increased to a maximum of 300 mg per day within 1 week.

Epilepsy:

Administer in 2 or 3 divided doses per day.

Begin dosing at 150 mg per day.

Maximum dose of 600 mg per day.

Fibromyalgia:

Administer in 2 divided doses per day.

Begin dosing at 150 mg per day.

May be increased to 300 mg per day within 1 week.

Maximum dose of 450 mg per day.

Post Herpetic Neuralgia:

Administer in 2 or 3 divided doses per day.

Begin dosing at 150 mg per day.

May be increased to 300 mg per day within 1 week.

Maximum dose of 600 mg per day.

Generalized Anxiety Disorder:

Administer in 2 or 3 divided doses per day.

Begin dosing at 150 mg per day.

Maximum dose of 600 mg per day.

Dose should be adjusted in patients with reduced renal function.

Administration in Renal Impairment:

Pregabalin clearance is directly proportional to creatinine clearance, so dosage reduction in patient with compromised renal function must be adjusted according to creatinine clearance (Clcr).

.

Discontinuation of Pregabalin:

In accordance with current clinical practice, if Pregabalin has to be discontinued, it is recommended to withdraw gradually over a minimum of 1 week.

Contraindications

Prey w in wit aii to Pregabalin or any of its components.

Side Effects

Dizziness, somnolence, vision blurred, fatigue, weight increased, dry mouth, ataxia, peripheral edema, diplopia, tremor, constipation, confusion, lethargy, memory impairment, appetite increased & oedema etc.

Pregnancy & Lactation

Pregnancy Category C: Breast-feeding is not recommended during treatment with Pregabalin.

Precautions & Warnings

It is advised not to drive a car or operating dangerous machineries. While taking Pregabalin, some patients with diabetes who gain weight may need to alter their diabetic medications. Alcohol should be avoided while taking this medicine. Patients with renal insufficiency should take Pregabalin with proper caution & dose adjustment should be done according to creatinine clearance.

Storage Conditions

Store in a dry place & away from light. Keep out of reach of children.

PG® • 6 x 4

৳ 90.00