Telfadin 120 Tablet: Each film coated tablet contains Fexofenadine Hydrochloride USP 120 mg.
Telfadin 180 Tablet: Each film coated tablet contains Fexofenadine Hydrochloride USP 180 mg.
Telfadin 50 ml Suspension: Each 5 ml suspension contains Fexofenadine Hydrochloride USP 30 mg.
Fexofenadine is a second-generation, long lasting H1-receptor antagonist which has a selective and peripheral H1-antagonistic action. Fexofenadine blocks the H1-receptor and thus prevents activation of cells by histamine in the GI tract, large blood vessels and bronchial smooth muscle. This leads to relief of the allergic symptoms. Unlike most other antihistamines, Fexofenadine does not enter the brain from the blood and therefore, does not cause drowsiness. Fexofenadine lacks the cardiotoxic potential, since it does not block the potassium channel involved in repolarization of cardiac cells.
It is indicated for the relief of symptoms associated with seasonal and perennial allergic rhinitis and chronic idiopathic urticaria.
Route of administration: Oral.
Adults:
Children:
With Medicine: Caution should be taken during the concomitant use of Fexofenadine Hydrochloride with the following drugs: erythromycin, ketoconazole and antacid containing aluminium and magnesium hydroxide gels.
With food & others: No adequate data are available.
Overdose:
In case of an overdose, standard measures to remove any unabsorbed drug should be employed. Symptomatic and supportive treatment is recommended. There has been no reported case of an acute overdose of Fexofenadine Hydrochloride.
Lactation: It is not known if Fexofenadine is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Fexofenadine is administered to a nursing woman.
Not recommended for children below 6 months of age.
Studies in the elderly, patients with hepatic impairment and patients with cardiac disease exposed to Fexofenadine showed no statistically significant differences compared to healthy individuals. As with most new drugs there is only limited data in the elderly and renally or hepatically impaired patients. Fexofenadine Hydrochloride should be administered with care in these special groups.
Store below 30° C temperature. Keep in a cool and dry place, away from light. Keep out of the reach of children.