Onecal-D: Each film coated tablet contains Calcium Carbonate BP 1250 mg equivalent to elemental Calcium 500 mg and Vitamin D₃ 200 IU as Cholecalciferol BP.
Calcium is needed for the formation of strong bones and healthy teeth and is involved in helping the blood to clot. It is also required to transmit nerve signals and help muscles work. Inadequate Calcium intake results in reduced bone mass and osteoporosis. Vitamin D3 is needed for calcium to be absorbed from the gut and deficiency can lead to low Calcium levels and subsequent weakening of bones. Calcium and vitamin D3 has synergistic effects on bone growth as well as in osteoporosis and in fraction prevention.
Calcium and Vitamin-D is used for the treatment of osteoporosis, osteomalacia, rickets, tetany, and parathyroid disease. Also used in raised calcium requirement for children and adolescents at times of rapid growth, inadequate intake of calcium in the diet due to malnutrition, prevention and treatment of osteoporosis, disorders of osteogenesis and tooth formation (in addition to specific treatment), latent tetany and during pregnancy and lactation. It is also used as routine supplement and phosphate binder in chronic renal failure.
a) Route of Administration: Oral One tablet twice daily with food or as directed by the physician.
a) With medicine: concurrent administration of Thiazide diuretics may increase the risk of hypercalcemia. Calcium salts reduce the absorption of a number of other drugs such as Biphosphonates, Fluoride, some Fluoroquinolones and Tetracyclines. b) With food & other: generally calcium & vitamin D₃ is well tolerated with food & others.
Overdose:
At high doses it may result in nausea, vomiting, dizziness, anorexia, abdominal cramps, headache, constipation, irritability etc. Treatment includes cessation of therapy and adequate rehydration.
Onecal-D should be used considering the risk benefit ratio.
Use of Calcium Carbonate in children and infants with chronic renal failure is both safe and effective.
Caution should be taken in patients with renal impairment, Sarcoidosis, Hypercalcemia and Hypercalciuria, Cardiac disease.
Store below 30° C. Protect from light and moisture. Keep all medicines out of reach of children.