Micosone Cream: Each g contains Miconazole Nitrate BP 20 mg & Hydrocortisone BP 10 mg.
Micosone Ointment: Each g contains Miconazole Nitrate BP 20 mg & Hydrocortisone BP 10 mg.
Micosone ® is a combination preparation of Miconazole Nitrate and Hydrocortisone which exhibits broad spectrum activity against pathogenic yeasts and dermatophytes and also effective against infection with gram-positive bacteria including many strains of Streptococcus and Staphylococcus susceptible to Miconazole. It also contains Hydrocortisone which possesses an antipruritic and antiallergic activity and also exhibits an antimitotic effect against human epidermal cells which may account for their effectiveness in the treatment of dermatoses such as psoriasis.
Adults : Micosone ® cream and ointment should be applied topically to the affected area 2-3 times a day. Children: Same as adults. Infants: Long term continuous topical corticosteroid therapy should be avoided. Micosone ® cream is particularly suitable for moist or weeping surfaces and for flexures of the body. Micosone ® ointment is suitable for dry, scaly lesions. The cream and ointment is indicated for the initial stages of treatment. Once the inflammatory symptoms have disappeared (after about 7 days), treatment can be continued where necessary with Miconazole cream. Occlusive dressing is usually only necessary in case of nail lesions. Elderly patients: Natural thinning of the skin occurs in the elderly, hence corticosteroid should be used sparingly and for short periods of time.
Systemic absorption of miconazole may enhance warfarin anticoagulant effect; avoid simultaneous application with other topical corticosteroids.
Miconazole is contraindicated in patients with known hypersensitivity to any of the ingredients. It is also contraindicated to patients with tubercular or viral infections of the skin or those caused by gram-negative bacteria.
Rare: Local skin irritation, hypersensitivity reactions.
Overdose
Topically applied corticosteroids can be absorbed in sufficient amounts to produce systemic effects. If accidental ingestion of large quantities of the product occurs, an appropriate method of gastric emptying may be used.
Category C. Minimal systemic absorption; use with caution during pregnancy only if clearly needed. Lactation: Excretion in human milk unknown; caution advised in nursing mothers.
Store below 25°C in a cool and dry place. Protect from light and moisture. Keep out of reach of children.