Exovate® Cream: Each gram contains Clobetasol Propionate USP 0.5 mg.
Exovate® Ointment: Each gram contains Clobetasol Propionate USP 0.5 mg.
Clobetasol Propionate is a very active topical corticosteroid.
A small quantity should be applied to the affected area once or twice daily until improvement occurs. Therapy should be discontinued when control is achieved. It is recommended that treatment should not be continued for more than two or four weeks without the patients’ condition being reviewed. If continuous steroid treatment is required a less potent preparation is required.
Skin atrophy especially with occlusion or in skin folds, hypercorticism. Provided the weekly dosage is less than 50g in adults, any pituitary-adrenal suppression is likely to be transient. Occasional hypersensitivity reactions.
No overdose related problem yet reported.
There is an inadequate evidence of safety in human pregnancy.
Long term continuous therapy with clobetasol should be avoided, particularly in infants and children, in whom adrenal suppression occurs readily. If Clobetasol is required for use in children, or on the face, it is recommended that the treatment should be reviewed weekly. The face, more than other areas of the body, may exhibit atrophic changes after prolonged treatment with potent topical corticosteroids. Clobetasol should be kept out of the eye as it may cause glaucoma. Topical steroid may be hazardous in psoriasis; careful patient supervision is important. Consider if infection spreads. Do not use near a naked flame.
Keep in a cool & dry place.