Duozol Ds Vet

Each bolus contains Triclabendazole INN 1800 mg and Levamisole Hydrochloride BP equivalent to Levamisole 1,200 mg.

Duozol Ds Vet is a combination formulation of triclabendazole and levamisole indicated for the treatment and control of fascioliasis, gastrointestinal roundworms, and lungworms in cattle, sheep, and goats. Triclabendazole functions by inhibiting the energy metabolism of helminths. Levamisole acts on the neuromuscular junctions of nematodes as a ganglionic nicotinic acetylcholine agonist, inducing muscular contraction and stimulating the parasympathetic and sympathetic ganglia of susceptible parasites. Additionally, levamisole interferes with carbohydrate metabolism in nematodes by blocking fumarate reduction and succinate oxidation. The combined pharmacological action results in paralysis of the parasite, facilitating its expulsion from the host.

Livestock:

Route of Administration: Oral (dissolve tablet in water as a drench, mix with molasses, or wrap in a banana leaf).

Or as directed by the registered Veterinarian.

Cimetidine, Praziquantel and Dexamethasone have been reported to increase the plasma levels of Albendazole active metabolite.

Enoxin Vet is well tolerated for poultry at the recommended dose. However, it may cause developmental cartilage abnormalities.

At the recommended dosage in pregnancy no harmful effect has been reported in pregnancy. Moreover, no embryotoxic or teratogenic effects on the fetus have been reported.

Adequate water should be fed during and after therapy.

Store in a cool and dry place. Protect from direct sunlight.