Diar 500 mg tablet: Each tablet contains Nitazoxanide INN 500 mg.
Diar powder for suspension: When reconstituted each 5 ml contains Nitazoxanide INN 100 mg.
Diar ® is an oral antidiarrheal preparation contains Nitazoxanide a synthetic antiprotozoal agent which is also effective in diarrhoea caused by Rotavirus. Nitazoxanide interfere with the pyruvate ferredoxin oxidoreductase (PFOR) enzyme-dependent electron transfer reaction which is essential to anaerobic energy metabolism.
Adults and adolescents (over 12 years) : 25 ml or 500 mg tablet every 12 hours for 3 days. Children (4 to 11 years) : 10 ml (200 mg) every 12 hours for 3 days. Children (1 to 3 years) : 5 ml (100 mg) every 12 hours for 3 days. It is important to take Nitazoxanide with food.
Highly bound to plasma protein: use caution when co-administering with other highly protein-bound medications (warfarin, phenytoin).
Hypersensitivity to Nitazoxanide or any other ingredient in the formulations. The safety and effectiveness of Nitazoxanide suspension in paediatric patients less than 1 year of age have not beenstudied so it should not be taken by children less than 1 year of age.
Common: Abdominal pain, headache, nausea, anorexia, flatulence, appetite increase, enlarged salivary glands. Rare: Rash, swelling, dizziness, itching.
Overdose
No Data
Category B. No adequate and well-controlled studies in pregnant women; use only if clearly needed. Lactation: Excretion in human milk unknown; caution should be exercised.
Store below 30°C in a cool, dry place. Protect from light and moisture. Keep out of reach of children.