Each 5 ml syrup contains Dextromethorphan Hydrobromide BP 20 mg, Phenylephrine Hydrochloride BP 10 mg, Triprolidine Hydrochloride BP 2.5 mg.
Delkof Plus syrup is a preparation of an antitussive, decongestant and antihistamine. It is a combination of Dextromethorphan, Phenylephrine and Triprolidine. Dextromethorphan is a cough suppressant, which has a central action on the cough centre in the medulla. Phenylephrine is a decongestant that shrinks blood vessels in the nasal passage. Triprolidine provides symptomatic relief of allergic rhinitis and common cold.
Delkof Plus is indicated for the symptomatic relief of unproductive cough in the following conditions:
Adults and children over 12 years: 1 teaspoonful (5 ml) four times a day.
Children: 6-12 years: 1/2 teaspoonful (2.5 ml) four times a day. Children below 6 years as recommended by the physician.
Concomitant use of this combination with other sympathomimetic agents such as decongestants, tricyclic antidepressant, appetite suppressant and amphetamine- like psychostimulant or with monoamine oxidase inhibitors, which interfere with the catabolism of sympathomimetic amines, can occasionally raise the blood pressure. Phenylephrine in this combination may partially reverse the antihypertensive action of drugs, which interfere with sympathetic activity including methyldopa, alpha-and beta-adrenergic blocking agents.
There are no specific data on their use during pregnancy and lactation. So this combination should be used with caution during pregnancy and only if clearly indicated.
This combination should be used with caution in patients taking antihypertensive, tricyclic antidepressant or other sympathomimetic agents. Caution should be taken in severe hepatic and renal impairment. It should not be used for persistent cough due to smoking, asthma or emphysema or where cough is accompanied by excessive secretions unless recommended by a physician.
Warning:
Drowsiness can occur. Do not drive or operate machinery during therapy.
Store at 15°C to 30°C in a dry place, protected from light. Keep out of reach of children.