Eye Ointment: Each gm contains 10 mg of Chloramphenicol BP in a special base. It is a sterile eye ointment.
Eye/Ear Drops: Each ml eye/ear drops contains Chloramphenicol BP 5 mg. It is a sterile eye / ear drops.
Chloramphenicol is a broad spectrum antibiotic, isolated in 1947 from Streptomyces Venezuelae. It is primarily bacteriostatic and acts by inhibition of protein synthesis. It has been noted that chloramphenicol is found in measurable amounts in the aqueous humor following local application to the eye. Development of resistance to Chloramphenicol is minimum for staphylococci and many other species of bacteria.
Route of administration: Eye/Ear.
A-Phenicol® Eye Ointment: A-Phenicol® eye ointment should be used every three hours. Administration should be continued day and night for the first 48 hours after which the interval between application may be increased and continued for at least 2 days after the eye appears normal.
A-Phenicol® Eye/Ear Drops: For eye: 2 drops of solution every 1 hour, until condition improves or instill 4 times daily depending on severity of infection. For ear: (Adult & Children): 2 or 3 drops in the affected ear 2-3 times daily. OR AS DIRECTED BY THE PHYSICIAN.
Concurrent therapy with other drugs that may cause bone marrow depression should be avoided.
Overdose:
A topical overdose of A-Phenicol may be flushed from the eye(s) with warm tap water.
Chloramphenicol has been assigned to pregnancy category C by FDA. Chloramphenicol should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Dosage adjustment may be necessary in new-born infants to reduce the risk of adverse effects. Prolonged use of Chloramphenicol is not advisable. Should not use this product for longer than 5 days at a time without doctor’s advice.
Ophthalmic ointments may retard corneal wound healing. So patients with corneal disease should take precautions while using this medicine.
Store below 30°C temperature & dry place, protected from light. Keep all medicines out of reach of children.