Each gram oral gel contains 20 mg Miconazole USP.
Miconazole is a synthetic imidazole anti-fungal agent with a broad spectrum of activity against pathogenic fungi (including yeast and dermatophytes) and gram-positive bacteria (*Staphylococcus* and *Streptococcus spp*). It may act by interfering with the permeability of the fungal cell membranes. Miconazole oral gel is incompletely absorbed from the gastrointestinal tract. Miconazole is inactivated in the body and 10-20% of an oral dose is excreted in the urine.
Oral treatment and prevention of fungal infections of the oropharynx and gastrointestinal tract.
For oral administration:
Dosage is based on 15 mg/kg/day after meal.
For localised lesions of the mouth, a small amount of A-Migel oral gel may be applied directly to the affected area with a clean finger 2-4 times daily. For topical treatment of the oropharynx, the gel should be kept in the mouth for as long as possible.
Treatment should be continued for up to 2 days after the symptoms have cleared.
For oral candidiasis, dental prostheses should be removed at night and brushed with the gel.
Or as Directed by the Physician:
In animals Miconazole has shown no teratogenic effects but is foetotoxic at high oral doses. However, as with other imidazoles, Miconazole Oral Gel should be avoided in pregnant women if possible. The potential hazards should be balanced against the possible benefits.
It is not known whether Miconazole is excreted in human milk. Caution should be exercised when prescribing Miconazole Oral Gel to nursing mothers.
In general, Miconazole is not highly toxic. In the event of accidental over dosage, vomiting and diarrhoea may occur.
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The concomitant use of Miconazole with anti-coagulant, anti-epileptic and anti-diabetic drugs increases the affectivity of these drugs. So dosage of Miconazole should be revised.
Store in a cool & dry place protected from light. Keep all medicines out of reach of children.